TLCD4-RWDD3

Across TCGA patient cohorts, TLCD4-RWDD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,164 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible TLCD4-RWDD3-associated GO terms across cancer lineages are Protein sumoylation, Microtubule organizing center organization, and Obsolete regulation of dosage compensation by inactivation of X chromosome. Each is linked with TLCD4-RWDD3 in more than 33 cancer types. Because this analysis shows association rather than direction, both TLCD4-RWDD3-to-partner and partner-to-TLCD4-RWDD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein sumoylation grouped by TLCD4-RWDD3-low versus TLCD4-RWDD3-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD4-RWDD3→partner) and Y-score (partner→TLCD4-RWDD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Protein sumoylation →	+0.107	+0.834	<.001	<.001	3	34
SCLC	Microtubule organizing center organization →	+0.086	+0.765	<.001	<.001	3	34
THYM	Obsolete regulation of dosage compensation by inactivation of X chromosome →	+0.089	+0.621	<.001	<.001	3	34
SCLC	Nuclear export →	+0.058	+0.515	<.001	<.001	3	34
SCLC	Protein localization to lysosome →	+0.111	+0.799	<.001	<.001	3	34
THYM	Vacuole organization →	+0.054	+0.740	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,164 associations by consensus.

Protein sumoylation by TLCD4-RWDD3 expression — SCLC

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