TK2

Across TCGA patient cohorts, TK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,767 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TK2-associated proteins across cancer lineages are CMTM4, RIOK1, and RPL38. Each is linked with TK2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TK2-to-partner and partner-to-TK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TK2 versus CMTM4 in PDAC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TK2→partner) and Y-score (partner→TK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CMTM4 →	+0.828	+0.341	<.001	.006	3	6
BRCA	RIOK1 →	-0.449	-0.587	<.001	<.001	3	5
OV	RPL38 →	-0.572	-0.517	.002	.002	3	5
BRCA	RPL5 →	-0.300	-0.693	<.001	<.001	3	5
LUAD	SMC2 →	-0.552	-0.528	<.001	<.001	3	5
LUAD	SMC4 →	-0.586	-0.565	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,767 associations by consensus.

TK2 vs CMTM4 — PDAC

Explore this scatter interactively →