TIPRL

Across TCGA patient cohorts, TIPRL protein abundance is significantly associated with the RNA expression of many other genes, with 11,162 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TIPRL-associated genes across cancer lineages are CACYBP, TADA1, and CCT3. Each is linked with TIPRL in more than 7 cancer types. Because this analysis shows association rather than direction, both TIPRL-to-partner and partner-to-TIPRL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIPRL versus CACYBP in LSCC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIPRL→partner) and Y-score (partner→TIPRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CACYBP →	+0.681	+0.234	<.001	<.001	3	8
HNSC	TADA1 →	+0.752	+0.227	<.001	<.001	3	8
HNSC	CCT3 →	+0.805	+0.207	<.001	<.001	3	8
HNSC	SNRPE →	+0.954	+0.255	<.001	<.001	3	8
HNSC	GORAB →	+0.764	+0.225	<.001	<.001	3	7
HNSC	PRKAB2 →	+0.655	+0.202	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,162 associations by consensus.

TIPRL vs CACYBP — LSCC

Explore this scatter interactively →