TIPIN

Across TCGA patient cohorts, TIPIN protein abundance is significantly associated with the RNA expression of many other genes, with 13,565 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TIPIN-associated genes across cancer lineages are PRC1, UNG, and CDCA5. Each is linked with TIPIN in more than 6 cancer types. Because this analysis shows association rather than direction, both TIPIN-to-partner and partner-to-TIPIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIPIN versus PRC1 in GBM, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIPIN→partner) and Y-score (partner→TIPIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRC1 →	+0.590	+0.523	<.001	<.001	3	7
HNSC	UNG →	+0.792	+0.883	<.001	<.001	3	7
UCEC	CDCA5 →	+1.048	+0.539	<.001	<.001	3	7
OV	MTBP →	+1.079	+0.960	.002	.009	3	7
HNSC	MASTL →	+0.867	+0.769	.006	<.001	3	6
LSCC	PAICS →	+0.806	+0.697	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,565 associations by consensus.

TIPIN vs PRC1 — GBM

Explore this scatter interactively →