TIPIN

Across TCGA cell cohorts, TIPIN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,524 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TIPIN-associated GO terms across cancer lineages are DNA replication initiation, DNA replication checkpoint signaling, and Regulation of mitotic nuclear division. Each is linked with TIPIN in more than 19 cancer types. Because this analysis shows association rather than direction, both TIPIN-to-partner and partner-to-TIPIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by TIPIN-low versus TIPIN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIPIN→partner) and Y-score (partner→TIPIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication initiation →	+0.214	+1.000	.001	<.001	3	20
BONE	DNA replication checkpoint signaling →	+0.232	+0.859	.001	<.001	3	19
SOFT_TISSUE	Regulation of mitotic nuclear division →	+0.134	+0.858	<.001	<.001	3	19
BONE	Meiotic cell cycle →	+0.110	+0.883	.003	<.001	3	19
KIDNEY	Protein localization to kinetochore →	+0.174	+0.951	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.183	+1.384	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,524 associations by consensus.

DNA replication initiation by TIPIN expression — BONE

Explore this box plot interactively →