TIMM8AP1

Across TCGA patient cohorts, TIMM8AP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,165 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TIMM8AP1-associated GO terms across cancer lineages are Negative regulation of granulocyte chemotaxis, Negative regulation of neutrophil migration, and Receptor-mediated endocytosis of virus by host cell. Each is linked with TIMM8AP1 in more than 23 cancer types. Because this analysis shows association rather than direction, both TIMM8AP1-to-partner and partner-to-TIMM8AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of granulocyte chemotaxis grouped by TIMM8AP1-low versus TIMM8AP1-high in BLCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM8AP1→partner) and Y-score (partner→TIMM8AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	Negative regulation of granulocyte chemotaxis →	+0.261	+1.019	<.001	<.001	3	24
BLCA	Negative regulation of neutrophil migration →	+0.135	+1.013	<.001	<.001	3	20
DLBC	Receptor-mediated endocytosis of virus by host cell →	+0.069	+0.720	.002	.003	2	19
ACC	Negative regulation of leukocyte chemotaxis →	+0.053	+1.353	.009	.007	1	20
TGCT	Cell-cell adhesion mediated by integrin →	+0.061	+0.738	<.001	<.001	3	18
MESO	Regulation of extracellular matrix disassembly →	+0.053	+1.881	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

Negative regulation of granulocyte chemotaxis by TIMM8AP1 expression — BLCA

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