TIMM8AP1

Across TCGA pan-cancer cohorts, TIMM8AP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TIMM8AP1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TIMM8AP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TIMM8AP1 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

THCA, KICH, and KIRC are the cancer types where TIMM8AP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TIMM8AP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	+3.552	<.001	10	view →
KICH	Female	All	−0.704	<.001	9	view →
KIRC	All	III,IV	+0.359	.002	9	view →
UCEC	All	All	−1.281	<.001	6	view →
LUAD	Female	All	+1.117	<.001	6	view →
BRCA	All	II,III,IV	−0.878	<.001	6	view →
LIHC	Male	All	+0.895	<.001	5	view →
LUSC	Female	All	−0.881	<.001	5	view →
HNSC	Female	II,III,IV	+1.065	.022	3	view →
ESCA	Male	All	+1.098	.012	2	view →
STAD	All	II,III,IV	+0.304	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TIMM8AP1–THCA

Open the THCA breakdown →