Q-omics provides the consensus-scored TIMM8AP1 profile across patient tissues and cancer cell-line models. TIMM8AP1 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, TIMM8AP1 is differentially expressed in 11, with the highest sampling consensus in THCA. Additionally, TIMM8AP1 RNA expression shows 14,306 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UVM, THCA, and TGCT as cancer lineages where TIMM8AP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TIMM8AP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TIMM8AP1 survival associations across molecular data types. TIMM8AP1 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TIMM8AP1 RNA expression–survival associations across cancer types. High TIMM8AP1 expression shows unfavorable associations in UVM, STAD, ACC, LUSC and LGG, but favorable associations in THCA. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for TIMM8AP1 RNA expression.
This table summarizes TIMM8AP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for TIMM8AP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TIMM8AP1 shows lower tumor expression in KICH, UCEC and BRCA and higher tumor expression in THCA, KIRC and LUAD. The THCA box plot shows higher TIMM8AP1 RNA expression in tumor versus normal tissue (log2 FC = +3.552, t-test p < 0.001).
This table shows molecular features associated with TIMM8AP1 in patient tissues and cancer cell lines. In patient samples, TIMM8AP1 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
