Across TCGA patient cohorts, TIMM23B mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TIMM23B-associated genes across cancer lineages are VTRNA3-1P, IGHD1-26, and IGHD6-6. Each is linked with TIMM23B in more than 1 cancer types. Because this analysis shows association rather than direction, both TIMM23B-to-partner and partner-to-TIMM23B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM23B→partner) and Y-score (partner→TIMM23B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	VTRNA3-1P →	+0.606	+5.594	<.001	.004	3	2
UCEC	IGHD1-26 →	+1.890	+5.484	<.001	.005	3	1
UCEC	IGHD6-6 →	+1.667	+5.420	<.001	.005	3	1
SKCM	MIR518E →	+0.407	+6.328	<.001	.001	3	1
SKCM	OR6K5P →	+0.041	+5.037	.001	.009	3	1
LUAD	RNU6-643P →	+0.434	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

TIMM23B survival (RNA) · tumor vs normal (RNA) · all TIMM23B data types