TIMM10

Across TCGA cell cohorts, TIMM10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,771 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TIMM10-associated GO terms across cancer lineages are DNA replication initiation, Positive regulation of G2/MI transition of meiotic cell cycle, and [2Fe-2S] cluster assembly. Each is linked with TIMM10 in more than 16 cancer types. Because this analysis shows association rather than direction, both TIMM10-to-partner and partner-to-TIMM10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by TIMM10-low versus TIMM10-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM10→partner) and Y-score (partner→TIMM10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA replication initiation →	+0.163	+0.841	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Positive regulation of G2/MI transition of meiotic cell cycle →	+0.138	+0.944	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	[2Fe-2S] cluster assembly →	+0.119	+1.146	<.001	<.001	3	13
STOMACH	Meiotic chromosome segregation →	+0.163	+1.009	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Chromosome localization →	+0.118	+1.198	.001	<.001	3	13
SOFT_TISSUE	Double-strand break repair via break-induced replication →	+0.204	+0.732	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,771 associations by consensus.

DNA replication initiation by TIMM10 expression — PANCREAS

Explore this box plot interactively →