TIMM10

Across TCGA pan-cancer cohorts, TIMM10 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of TIMM10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TIMM10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TIMM10 is over-expressed in tumor.

KIRC, COAD, and BLCA are the cancer types where TIMM10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TIMM10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.589	<.001	12	view →
COAD	Female	All	+1.179	<.001	10	view →
BLCA	All	III,IV	+0.774	<.001	10	view →
LIHC	Male	II,III,IV	+1.058	<.001	9	view →
LUSC	All	II,III,IV	+0.897	<.001	8	view →
HNSC	Male	IV	+0.770	<.001	8	view →
LUAD	Female	II,III,IV	+0.674	<.001	7	view →
UCEC	All	II,III,IV	+0.907	<.001	6	view →
STAD	All	II,III,IV	+0.856	<.001	6	view →
BRCA	All	III,IV	+0.627	<.001	6	view →
CHOL	Female	All	+1.113	.010	2	view →
ESCA	All	All	+0.947	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

TIMM10–KIRC

Open the KIRC breakdown →