TICRR

Across TCGA patient cohorts, TICRR RNA expression is significantly associated with the protein abundance of many other proteins, with 28,166 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TICRR-associated proteins across cancer lineages are RRM2, SMC2, and SMC4. Each is linked with TICRR in more than 9 cancer types. Because this analysis shows association rather than direction, both TICRR-to-partner and partner-to-TICRR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TICRR versus RRM2 in LUAD, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TICRR→partner) and Y-score (partner→TICRR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RRM2 →	+0.974	+1.069	<.001	<.001	3	10
LSCC	SMC2 →	+0.716	+1.205	<.001	<.001	3	10
LUAD	SMC4 →	+0.685	+1.099	<.001	<.001	3	10
LSCC	FEN1 →	+0.553	+0.968	<.001	<.001	3	10
LUAD	KPNA2 →	+0.720	+1.071	<.001	<.001	3	10
BRCA	RIF1_S782 →	+1.163	+0.985	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,166 associations by consensus.

TICRR vs RRM2 — LUAD

Explore this scatter interactively →