TICRR

Across TCGA pan-cancer cohorts, TICRR RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of TICRR’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where TICRR RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TICRR is over-expressed in tumor.

BLCA, HNSC, and COAD are the cancer types where TICRR tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TICRR RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+1.948	<.001	12	view →
HNSC	Male	All	+1.328	<.001	11	view →
COAD	All	IV	+1.312	<.001	11	view →
KIRP	All	III,IV	+0.777	<.001	11	view →
STAD	All	III,IV	+2.128	<.001	10	view →
LUAD	Male	III,IV	+1.623	<.001	9	view →
KIRC	Male	IV	+0.579	<.001	9	view →
LUSC	Male	III,IV	+2.834	<.001	8	view →
UCEC	All	III,IV	+2.632	<.001	8	view →
LIHC	Female	II,III,IV	+0.697	<.001	8	view →
BRCA	All	II,III,IV	+1.137	<.001	6	view →
READ	All	All	+1.329	.002	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

TICRR–BLCA

Open the BLCA breakdown →