TIA1

Across TCGA patient cohorts, TIA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,530 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TIA1-associated proteins across cancer lineages are SNRPD3, HNRNPLL, and TRIM28. Each is linked with TIA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TIA1-to-partner and partner-to-TIA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIA1 versus SNRPD3 in PDAC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TIA1→partner) and Y-score (partner→TIA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SNRPD3 →	+0.436	+0.334	.001	.004	3	7
LSCC	HNRNPLL →	+0.261	+0.717	<.001	<.001	3	7
LSCC	TRIM28 →	+0.379	+0.551	<.001	<.001	3	7
GBM	SF3B3 →	+0.296	+0.665	<.001	<.001	3	6
LSCC	SIN3A →	+0.269	+0.567	<.001	<.001	3	6
GBM	SMARCC2 →	+0.329	+0.414	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,530 associations by consensus.

TIA1 vs SNRPD3 — PDAC

Explore this scatter interactively →