THPO

Across TCGA patient cohorts, THPO RNA expression is significantly associated with the protein abundance of many other proteins, with 14,172 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible THPO-associated proteins across cancer lineages are VCAN, MAP1A, and SARM1. Each is linked with THPO in more than 5 cancer types. Because this analysis shows association rather than direction, both THPO-to-partner and partner-to-THPO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THPO versus VCAN in OV, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THPO→partner) and Y-score (partner→THPO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VCAN →	+1.019	+0.300	<.001	<.001	3	6
HNSC	MAP1A →	+0.683	+0.418	<.001	<.001	3	6
OV	SARM1 →	+0.492	+0.365	<.001	<.001	3	6
OV	SNX9 →	+0.550	+0.428	<.001	<.001	3	6
BRCA	SSC5D →	+0.731	+0.753	<.001	<.001	3	5
OV	TIMM44 →	-0.547	-0.295	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,172 associations by consensus.

THPO vs VCAN — OV

Explore this scatter interactively →