Across TCGA patient cohorts, THEM5 RNA expression is significantly associated with the RNA expression of many other genes, with 17,114 significant associations in total. UVM shows the largest number of these associations.

The most reproducible THEM5-associated genes across cancer lineages are C2CD4D-AS1, C2CD4D, and ARHGEF11. Each is linked with THEM5 in more than 32 cancer types. Because this analysis shows association rather than direction, both THEM5-to-partner and partner-to-THEM5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THEM5→partner) and Y-score (partner→THEM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PCPG	C2CD4D-AS1 →	+3.226	+3.022	<.001	<.001	3	33
PCPG	C2CD4D →	+1.555	+2.820	<.001	<.001	3	31
THYM	ARHGEF11 →	+1.247	+1.116	<.001	<.001	3	25
CHOL	THEM4 →	+1.554	+1.847	<.001	.001	3	25
UVM	DSTYK →	+1.364	+1.254	<.001	<.001	3	24
LGG	SNHG28 →	+0.803	+1.148	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,114 associations by consensus.

Exploration

THEM5 survival (RNA) · tumor vs normal (RNA) · all THEM5 data types