C2CD4D-AS1

associated omics data
C2CD4D and THEM5 antisense RNA 1Genealiases: []

Q-omics provides the consensus-scored C2CD4D-AS1 profile across patient tissues and cancer cell-line models. C2CD4D-AS1 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, C2CD4D-AS1 is differentially expressed in 9, with the highest sampling consensus in LUAD. Additionally, C2CD4D-AS1 RNA expression shows 18,525 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight HNSC, LUAD, and UVM as cancer lineages where C2CD4D-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes C2CD4D-AS1 survival associations across molecular data types. C2CD4D-AS1 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
C2CD4D-AS1 data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier22HNSC (166)view →
This table ranks reproducible C2CD4D-AS1 RNA expression–survival associations across cancer types. High C2CD4D-AS1 expression shows unfavorable associations in LGG, KIRP and UVM, but favorable associations in HNSC, SKCM and KIRC. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for C2CD4D-AS1 RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSMedianAll0.6620.541<.001166view →
SKCMDFSTertileAll0.6880.553<.001103view →
LGGOSMedianAll0.3780.517<.00143view →
KIRCDFSQuartileAll0.7300.562.00134view →
KIRPOSQuartileIII,IV0.1110.860.00532view →
UVMDFSTertileII,III,IV0.4860.796.00727view →
Pink = unfavorable, green = favorable. all 22 lineages →

C2CD4D-AS1-HNSC (DFS)

Kaplan–Meier survival curve for C2CD4D-AS1 RNA expression in HNSC: high vs low expression groups.

Explore this curve interactively →

Tumor vs Normal expression

This table summarizes C2CD4D-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in LUAD for RNA.
C2CD4D-AS1 data typeExpression analysisLineage consensusLineage of highest sampling consensus
RNABox plot9LUAD (11)view →
This table ranks reproducible tumor–normal expression differences for C2CD4D-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. C2CD4D-AS1 shows lower tumor expression in BRCA and KICH and higher tumor expression in LUAD, LIHC, BLCA and STAD. The LUAD box plot shows higher C2CD4D-AS1 RNA expression in tumor versus normal tissue (log2 FC = +2.110, t-test p < 0.001).
LineageGenderStageFold-changepSampling consensus
LUADMaleII,III,IV+2.110<.00111view →
LIHCMaleAll+2.265<.0019view →
BLCAAllIII,IV+1.376.0106view →
STADAllAll+1.126.0016view →
BRCAFemaleAll−0.301.0176view →
KICHFemaleAll−1.209<.0015view →
Green = repressed in tumor. all 9 lineages →

C2CD4D-AS1-LUAD

Tumor-vs-normal expression box plot for C2CD4D-AS1 in LUAD.

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Cross-omics associations

This table shows molecular features associated with C2CD4D-AS1 in patient tissues and cancer cell lines. In patient samples, C2CD4D-AS1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
RNA18,525UVM (7889)view →
Protein (mass-spec)8,840LUAD (3156)view →