C2CD4D-AS1

Across TCGA pan-cancer cohorts, C2CD4D-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of C2CD4D-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where C2CD4D-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C2CD4D-AS1 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

LUAD, LIHC, and BLCA are the cancer types where C2CD4D-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C2CD4D-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	+2.110	<.001	11	view →
LIHC	Male	All	+2.265	<.001	9	view →
BLCA	All	III,IV	+1.376	.010	6	view →
STAD	All	All	+1.126	.001	6	view →
BRCA	Female	All	−0.301	.017	6	view →
KICH	Female	All	−1.209	<.001	5	view →
CHOL	All	II,III,IV	+4.575	.014	4	view →
KIRP	All	All	−0.663	.017	4	view →
PRAD	All	All	+0.261	.027	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

C2CD4D-AS1–LUAD

Open the LUAD breakdown →