C2CD4D-AS1

Across TCGA pan-cancer cohorts, C2CD4D-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated C2CD4D-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher C2CD4D-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated C2CD4D-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, SKCM, and LGG are the cancer types where C2CD4D-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.662	0.541	<.001	166	view →
SKCM	DFS	Tertile	All	0.688	0.553	<.001	103	view →
LGG	OS	Median	All	0.378	0.517	<.001	43	view →
KIRC	DFS	Quartile	All	0.730	0.562	.001	34	view →
KIRP	OS	Quartile	III,IV	0.111	0.860	.005	32	view →
UVM	DFS	Tertile	II,III,IV	0.486	0.796	.007	27	view →
GBM	DFS	Tertile	All	0.181	0.383	.005	24	view →
MESO	DFS	Median	All	0.337	0.190	.015	22	view →
LUSC	OS	Median	All	0.330	0.455	.014	17	view →
READ	OS	Tertile	III,IV	0.842	0.261	.003	15	view →
UCS	DFS	Median	IV	0.811	0.514	.039	12	view →
ESCA	OS	Median	All	0.543	1.000	.026	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

C2CD4D-AS1–HNSC (DFS)

Open the HNSC breakdown →