THAP9-AS1

Across TCGA pan-cancer cohorts, THAP9-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated THAP9-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher THAP9-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated THAP9-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.

ACC, KICH, and LGG are the cancer types where THAP9-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.288	0.889	<.001	78	view →
KICH	OS	Quartile	II,III,IV	0.308	0.942	.002	77	view →
LGG	DFS	Median	All	0.671	0.799	<.001	47	view →
UVM	DFS	Quartile	III,IV	0.183	0.790	.003	32	view →
PRAD	DFS	Tertile	All	0.707	0.855	<.001	30	view →
LIHC	DFS	Tertile	All	0.447	0.646	<.001	25	view →
BLCA	OS	Tertile	II,III,IV	0.504	0.226	.007	19	view →
HNSC	OS	Quartile	IV	0.770	0.571	.012	18	view →
SARC	OS	Tertile	All	0.339	0.713	<.001	14	view →
KIRC	DFS	Median	All	0.810	0.912	.003	14	view →
CESC	DFS	Tertile	III,IV	0.192	0.677	.016	12	view →
SKCM	DFS	Quartile	III,IV	0.342	0.804	.001	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

THAP9-AS1–ACC (OS)

Open the ACC breakdown →