THAP9-AS1

Across TCGA pan-cancer cohorts, THAP9-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of THAP9-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where THAP9-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types THAP9-AS1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, STAD, and HNSC are the cancer types where THAP9-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in THAP9-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.733	<.001	10	view →
STAD	All	II,III,IV	+0.972	<.001	8	view →
HNSC	Male	III,IV	+0.880	.001	8	view →
COAD	Male	II,III,IV	+0.825	<.001	6	view →
CHOL	Female	All	+2.586	<.001	5	view →
LUAD	All	All	+0.365	<.001	5	view →
UCEC	All	II,III,IV	+0.666	.039	4	view →
LIHC	All	All	+0.419	.001	4	view →
LUSC	All	All	+0.310	.007	3	view →
THCA	All	All	−0.263	.010	3	view →
ESCA	Female	All	+0.936	.002	2	view →
BLCA	Male	III,IV	+0.865	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

THAP9-AS1–KIRC

Open the KIRC breakdown →