Q-omics provides the consensus-scored THAP9-AS1 profile across patient tissues and cancer cell-line models. THAP9-AS1 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, THAP9-AS1 is differentially expressed in 15, with the highest sampling consensus in KIRC. Additionally, THAP9-AS1 RNA expression shows 18,925 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ACC, KIRC, and UVM as cancer lineages where THAP9-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for THAP9-AS1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes THAP9-AS1 survival associations across molecular data types. THAP9-AS1 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible THAP9-AS1 RNA expression–survival associations across cancer types. High THAP9-AS1 expression shows unfavorable associations in ACC, KICH, LGG, UVM, PRAD and LIHC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for THAP9-AS1 RNA expression.
This table summarizes THAP9-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for THAP9-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. THAP9-AS1 shows higher tumor expression in KIRC, STAD, HNSC, COAD, CHOL and LUAD. The KIRC box plot shows higher THAP9-AS1 RNA expression in tumor versus normal tissue (log2 FC = +0.733, t-test p < 0.001).
This table shows molecular features associated with THAP9-AS1 in patient tissues and cancer cell lines. In patient samples, THAP9-AS1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, THAP9-AS1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in NCI60_ALL.
