TGIF2LY

Across TCGA cell cohorts, TGIF2LY RNA expression is significantly associated with the mutation status of many other genes, with 56 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TGIF2LY-associated genes across cancer lineages are SPG11, TMEM132C, and OLFM1. Each is linked with TGIF2LY in more than 1 cancer types. Because this analysis shows association rather than direction, both TGIF2LY-to-partner and partner-to-TGIF2LY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPG11 grouped by TGIF2LY-low versus TGIF2LY-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGIF2LY→partner) and Y-score (partner→TGIF2LY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	SPG11 →	+4.643	+0.056	.008	<.001	3	2
BLOOD_Leukemia	TMEM132C →	+2.536	+0.181	.009	<.001	3	2
LUNG_NSCLC_LUSC	OLFM1 →	+4.643	+0.056	.008	<.001	3	1
LUNG_NSCLC_LUSC	CA1 →	+4.643	+0.056	.008	<.001	3	1
LUNG_NSCLC_LUSC	POGZ →	+4.643	+0.056	.008	<.001	3	1
LUNG_NSCLC_LUSC	ITGB2 →	+4.643	+0.056	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

SPG11 by TGIF2LY expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →