TGIF2-RAB5IF

Across TCGA patient cohorts, TGIF2-RAB5IF RNA expression is significantly associated with the go_rna of many other GO terms, with 7,114 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TGIF2-RAB5IF-associated GO terms across cancer lineages are Meiotic chromosome condensation, Positive regulation of centriole replication, and Pore complex assembly. Each is linked with TGIF2-RAB5IF in more than 23 cancer types. Because this analysis shows association rather than direction, both TGIF2-RAB5IF-to-partner and partner-to-TGIF2-RAB5IF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic chromosome condensation grouped by TGIF2-RAB5IF-low versus TGIF2-RAB5IF-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGIF2-RAB5IF→partner) and Y-score (partner→TGIF2-RAB5IF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Meiotic chromosome condensation →	+0.130	+0.338	<.001	<.001	3	24
UCS	Positive regulation of centriole replication →	+0.059	+0.682	<.001	<.001	3	23
ESCA	Pore complex assembly →	+0.062	+0.227	.004	<.001	3	23
THYM	Regulation of chromosome condensation →	+0.091	+0.259	<.001	.001	2	24
ESCA	Centriole assembly →	+0.055	+0.253	.004	<.001	2	24
TGCT	Maintenance of cell number →	+0.039	+0.401	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,114 associations by consensus.

Meiotic chromosome condensation by TGIF2-RAB5IF expression — THYM

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