TGFBR1

Across TCGA cell cohorts, TGFBR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,771 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TGFBR1-associated GO terms across cancer lineages are Parathyroid gland development, Positive regulation of extracellular matrix assembly, and Regulation of tight junction disassembly. Each is linked with TGFBR1 in more than 19 cancer types. Because this analysis shows association rather than direction, both TGFBR1-to-partner and partner-to-TGFBR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Parathyroid gland development grouped by TGFBR1-low versus TGFBR1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFBR1→partner) and Y-score (partner→TGFBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Parathyroid gland development →	+1.599	+1.387	<.001	<.001	3	20
OESOPHAGUS	Positive regulation of extracellular matrix assembly →	+0.208	+1.330	<.001	.005	3	16
LIVER	Regulation of tight junction disassembly →	+1.309	+1.695	<.001	.002	3	15
LIVER	Positive regulation of tight junction disassembly →	+1.309	+1.695	<.001	.002	3	15
LUNG_NSCLC_LUSC	Ventricular trabecula myocardium morphogenesis →	+0.207	+1.834	<.001	<.001	3	15
LIVER	Trophoblast cell migration →	+0.486	+2.133	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,771 associations by consensus.

Parathyroid gland development by TGFBR1 expression — BLOOD_Myeloma

Explore this box plot interactively →