TFE3

Across TCGA patient cohorts, TFE3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,651 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TFE3-associated proteins across cancer lineages are PLS3, C1R, and C1S. Each is linked with TFE3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TFE3-to-partner and partner-to-TFE3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TFE3 versus PLS3 in BRCA, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TFE3→partner) and Y-score (partner→TFE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLS3 →	+0.444	+0.316	.002	.005	3	6
CCRCC	C1R →	+0.620	+0.294	<.001	<.001	3	5
BRCA	C1S →	+0.601	+0.467	<.001	<.001	3	5
OV	CRTAP →	+0.490	+0.724	<.001	<.001	3	5
GBM	ITGA5 →	+0.417	+0.349	.001	.003	1	7
BRCA	LRP1 →	+0.510	+0.467	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,651 associations by consensus.

TFE3 vs PLS3 — BRCA

Explore this scatter interactively →