TFDP1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TFDP1 mutation is significantly associated with the RNA expression of many other genes, with 3,008 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TFDP1-associated genes across cancer lineages are GEMIN4, RCC1, and SHMT2. Each is linked with TFDP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TFDP1-to-partner and partner-to-TFDP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFDP1→partner) and Y-score (partner→TFDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGEMIN4 →+0.404+2.524<.001<.00132
UCECRCC1 →+0.381+3.180.001<.00132
UCECSHMT2 →+0.472+1.809<.001.00132
UCECRWDD4 →+0.375+1.415.001.00932
UCECTRAIP →+0.449+1.797<.001<.00132
UCECNR2C2AP →+0.377+1.776<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,008 associations by consensus.

Exploration