transcription factor A, mitochondrial pseudogene 1Genealiases: MTTF1 · TCF6L1
Q-omics provides the consensus-scored TFAMP1 profile across patient tissues and cancer cell-line models. TFAMP1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, TFAMP1 is differentially expressed in 4, with the highest sampling consensus in UCEC. Additionally, TFAMP1 RNA expression shows 12,467 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KIRP, UCEC, and UVM as cancer lineages where TFAMP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TFAMP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TFAMP1 survival associations across molecular data types. TFAMP1 RNA expression shows survival associations in the most cancer types (21), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TFAMP1 RNA expression–survival associations across cancer types. High TFAMP1 expression shows unfavorable associations in KIRP, ACC, KIRC, UVM and LUAD, but favorable associations in READ. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for TFAMP1 RNA expression.
This table summarizes TFAMP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for TFAMP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TFAMP1 shows higher tumor expression in UCEC, KIRP, COAD and KIRC. The UCEC box plot shows higher TFAMP1 RNA expression in tumor versus normal tissue (log2 FC = +0.200, t-test p = .037).
This table shows molecular features associated with TFAMP1 in patient tissues and cancer cell lines. In patient samples, TFAMP1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
