TFAMP1

Across TCGA patient cohorts, TFAMP1 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TFAMP1-associated genes across cancer lineages are GSK-3_pS9, Ku80, and p38-MAPK_pT180_Y182. Each is linked with TFAMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TFAMP1-to-partner and partner-to-TFAMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK-3_pS9 grouped by TFAMP1-low versus TFAMP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFAMP1→partner) and Y-score (partner→TFAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GSK-3_pS9 →	-0.510	-2.999	.008	.035	3	1
UCEC	Ku80 →	+0.249	+2.472	.029	.011	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.690	-3.169	.001	.019	3	1
UCEC	PDCD4 →	-0.632	-2.459	.005	.020	3	1
UCEC	Src_pY527 →	-0.568	-3.159	.006	.019	3	1
UCEC	BRD4 →	+0.307	+2.329	.022	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

GSK-3_pS9 by TFAMP1 expression — UCEC

Explore this box plot interactively →