TEX50

Across TCGA cell cohorts, TEX50 RNA expression is significantly associated with the mutation status of many other genes, with 150 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TEX50-associated genes across cancer lineages are MAP3K4, NCAN, and FER1L6. Each is linked with TEX50 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX50-to-partner and partner-to-TEX50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAP3K4 grouped by TEX50-low versus TEX50-high in LUNG_SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX50→partner) and Y-score (partner→TEX50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	MAP3K4 →	+4.643	+0.030	.004	<.001	3	2
SOFT_TISSUE	NCAN →	+4.392	+0.016	.004	<.001	3	2
SOFT_TISSUE	FER1L6 →	+4.392	+0.016	.004	<.001	3	2
SKIN	PCDH7 →	+3.684	+0.131	.006	<.001	3	2
LUNG_SCLC	SEC14L5 →	+4.643	+0.030	.004	<.001	3	2
LUNG_SCLC	OR2AK2 →	+4.643	+0.030	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 150 associations by consensus.

MAP3K4 by TEX50 expression — LUNG_SCLC

Explore this box plot interactively →