Across TCGA pan-cancer cohorts, TEX50 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of TEX50’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where TEX50 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TEX50 is over-expressed in tumor.
STAD are the cancer types where TEX50 tumor–normal differential expression is most reproducible.