TEX48

Across TCGA cell cohorts, TEX48 RNA expression is significantly associated with the go_rna of many other GO terms, with 768 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX48-associated GO terms across cancer lineages are Apoptotic signaling pathway, Amyloid-beta formation, and Intrinsic apoptotic signaling pathway. Each is linked with TEX48 in more than 5 cancer types. Because this analysis shows association rather than direction, both TEX48-to-partner and partner-to-TEX48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Apoptotic signaling pathway grouped by TEX48-low versus TEX48-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX48→partner) and Y-score (partner→TEX48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Apoptotic signaling pathway →	+0.043	+0.239	<.001	.002	3	6
LUNG_NSCLC_LUAD	Amyloid-beta formation →	+0.083	+0.491	<.001	.007	3	5
LARGE_INTESTINE	Intrinsic apoptotic signaling pathway →	+0.038	+0.191	.001	.008	2	6
OVARY	Lymphocyte apoptotic process →	+0.121	+0.098	<.001	.009	3	4
LARGE_INTESTINE	Positive regulation of ATP biosynthetic process →	+0.106	+0.181	<.001	.003	3	4
LARGE_INTESTINE	Regulation of CD4-positive, alpha-beta T cell differentiation →	+0.054	+0.192	<.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 768 associations by consensus.

Apoptotic signaling pathway by TEX48 expression — LARGE_INTESTINE

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