TEX48

Across TCGA pan-cancer cohorts, TEX48 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated TEX48 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher TEX48 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TEX48 expression acts as an unfavorable survival marker, although some lineages such as STAD and UCS show a favorable association.

UVM, KIRP, and READ are the cancer types where TEX48 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Quartile	III,IV	0.219	0.841	<.001	37	view →
KIRP	OS	Quartile	All	0.849	0.957	<.001	34	view →
READ	OS	Median	All	0.418	0.923	.003	30	view →
STAD	DFS	Quartile	IV	0.867	0.184	.004	24	view →
UCS	DFS	Quartile	III,IV	0.604	0.162	.016	20	view →
THYM	OS	Median	All	0.921	1.000	.013	12	view →
ACC	OS	Tertile	IV	0.301	0.651	.010	11	view →
THCA	DFS	Quartile	II,III,IV	0.780	0.933	.021	9	view →
SKCM	DFS	Tertile	IV	0.111	0.694	.004	8	view →
SCLC	DFS	Median	IV	0.630	0.164	.022	8	view →
BRCA	OS	Tertile	IV	0.658	0.161	.018	7	view →
GBM	OS	Quartile	All	0.539	0.375	.012	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

TEX48–UVM (DFS)

Open the UVM breakdown →