TEX48

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, TEX48 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of TEX48’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TEX48 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TEX48 is over-expressed in tumor.

KIRC, LUAD, and BRCA are the cancer types where TEX48 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TEX48 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCAllAll+0.032.0018view →
LUADMaleII,III,IV+0.931<.0017view →
BRCAAllII,III,IV+0.188.0044view →
COADAllAll+0.127.0164view →
LIHCAllAll+0.045.0044view →
HNSCAllIII,IV+0.130.0223view →
LUSCAllAll+0.209<.0012view →
KIRPFemaleAll+0.197.0152view →
PRADAllAll+0.179<.0012view →
STADMaleII,III,IV+0.098.0222view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

TEX48–KIRC

Tumor-vs-normal expression box plot for TEX48 RNA in KIRC.

Open the KIRC breakdown →

Exploration