Across TCGA patient cohorts, TEX45 mutation is significantly associated with the RNA expression of many other genes, with 548 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX45-associated genes across cancer lineages are RN7SL429P, RN7SL386P, and RN7SL343P. Each is linked with TEX45 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX45-to-partner and partner-to-TEX45 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX45→partner) and Y-score (partner→TEX45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL429P →	+0.426	+5.404	<.001	.005	3	2
SKCM	RN7SL386P →	+0.089	+3.291	<.001	.006	3	2
SKCM	RN7SL343P →	+0.072	+4.485	<.001	.004	3	2
LUSC	ATP5MFP3 →	+0.323	+5.404	<.001	.005	3	2
LUSC	RSL24D1P5 →	+0.109	+5.792	<.001	.003	3	2
SKCM	OR5J7P →	+0.045	+3.993	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 548 associations by consensus.

Exploration

TEX45 survival (RNA) · tumor vs normal (RNA) · all TEX45 data types