Across TCGA pan-cancer cohorts, TEX45 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated TEX45 data layer.

The strongest signal is observed in small cell lung cancer (SCLC), where higher TEX45 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TEX45 expression acts as an unfavorable survival marker, although some lineages such as SCLC and BRCA show a favorable association.

SCLC, KIRC, and BRCA are the cancer types where TEX45 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Tertile	All	0.597	0.214	.004	72	view →
KIRC	OS	Tertile	II,III,IV	0.603	0.744	.013	54	view →
BRCA	DFS	Median	IV	0.791	0.343	.003	51	view →
THCA	DFS	Quartile	III,IV	0.429	0.966	.001	40	view →
BLCA	OS	Median	II,III,IV	0.776	0.663	.009	28	view →
KIRP	OS	Quartile	III,IV	0.177	0.742	.005	28	view →
HNSC	DFS	Median	All	0.497	0.227	.003	27	view →
THYM	OS	Median	All	0.921	1.000	.012	22	view →
UCEC	OS	Median	All	0.781	0.592	.003	22	view →
READ	DFS	Median	III,IV	0.811	0.405	.005	19	view →
LIHC	OS	Median	All	0.698	0.858	<.001	17	view →
UVM	OS	Median	III,IV	0.650	0.919	.022	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

Exploration

Same gene, other analysis: TEX45 tumor-vs-normal RNA expression · all TEX45 data types