TEX37

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TEX37 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TEX37-associated genes across cancer lineages are KCNA10, OR51T1, and OR4A16. Each is linked with TEX37 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX37-to-partner and partner-to-TEX37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNA10 grouped by TEX37-low versus TEX37-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX37→partner) and Y-score (partner→TEX37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaKCNA10 →+0.006+5.539.001.00331
BLOOD_LeukemiaOR51T1 →+0.099+4.922<.001.00931
BLOOD_LeukemiaOR4A16 →+0.069+6.569<.001<.00131
BLOOD_LeukemiaNUPR2 →+0.067+5.539<.001.00331
BLOOD_LeukemiaFAM47B →+0.019+5.969<.001.00131
BLOOD_LeukemiaKRTAP5-3 →+0.038+4.922<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

KCNA10 by TEX37 expression — BLOOD_Leukemia

Box plot of KCNA10 in TEX37-low vs TEX37-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration