TEX37

Across TCGA pan-cancer cohorts, TEX37 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated TEX37 data layer compared with 2 for mutation status.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher TEX37 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TEX37 expression acts as an unfavorable survival marker, although some lineages such as OV and LAML show a favorable association.

CHOL, UVM, and UCEC are the cancer types where TEX37 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Tertile	All	0.376	0.797	<.001	135	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	99	view →
UCEC	OS	Quartile	II,III,IV	0.750	0.893	.003	76	view →
LUSC	OS	Tertile	II,III,IV	0.273	0.471	.001	70	view →
OV	OS	Median	All	0.735	0.643	.001	40	view →
BRCA	OS	Tertile	IV	0.106	0.791	<.001	36	view →
KIRC	OS	Tertile	All	0.527	0.660	.007	22	view →
ACC	OS	Tertile	All	0.620	0.907	.006	21	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
LAML	DFS	Tertile	All	0.621	0.334	.016	18	view →
BLCA	OS	Tertile	IV	0.318	0.625	.019	18	view →
THCA	OS	Tertile	III,IV	0.773	0.952	.032	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

TEX37–CHOL (OS)

Open the CHOL breakdown →