TEX12

Across TCGA patient cohorts, TEX12 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX12-associated genes across cancer lineages are CTHRC1P1, NUDT4P2, and RN7SL828P. Each is linked with TEX12 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX12-to-partner and partner-to-TEX12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTHRC1P1 grouped by TEX12-low versus TEX12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX12→partner) and Y-score (partner→TEX12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CTHRC1P1 →	+0.158	+3.957	<.001	.002	3	1
UCEC	NUDT4P2 →	+0.091	+3.747	<.001	.003	3	1
UCEC	RN7SL828P →	+0.161	+3.344	.007	.007	3	1
UCEC	MIR6864 →	+0.939	+3.324	<.001	.002	3	1
UCEC	MIR6895 →	+1.152	+3.895	<.001	.001	3	1
UCEC	IL21 →	+0.171	+2.763	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

CTHRC1P1 by TEX12 expression — UCEC

Explore this box plot interactively →