TEX12

Across TCGA pan-cancer cohorts, TEX12 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TEX12 data layer compared with 2 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher TEX12 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TEX12 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LAML show a favorable association.

MESO, SCLC, and ACC are the cancer types where TEX12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Quartile	All	0.279	0.529	.006	54	view →
SCLC	DFS	Median	II,III,IV	0.223	0.603	.002	52	view →
ACC	OS	Tertile	All	0.337	0.793	<.001	28	view →
LUAD	DFS	Median	IV	0.817	0.412	.009	28	view →
LAML	DFS	Tertile	All	0.544	0.184	.005	24	view →
KIRC	DFS	Quartile	All	0.508	0.714	.001	19	view →
KIRP	DFS	Tertile	III,IV	0.184	0.693	.005	19	view →
LGG	OS	Quartile	All	0.351	0.703	<.001	16	view →
CHOL	OS	Median	III,IV	1.000	0.286	.008	12	view →
THCA	OS	Median	II,III,IV	0.958	1.000	.005	11	view →
READ	OS	Tertile	All	1.000	0.630	.011	11	view →
HNSC	OS	Median	All	0.493	0.335	.015	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TEX12–MESO (DFS)

Open the MESO breakdown →