TEX12

Across TCGA pan-cancer cohorts, TEX12 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of TEX12’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where TEX12 RNA is repressed in tumor relative to normal tissue. In most cancer types TEX12 is over-expressed in tumor, although a few such as BLCA and LUSC show the opposite, repressed pattern.

BLCA, LUSC, and BRCA are the cancer types where TEX12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TEX12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	−0.231	<.001	9	view →
LUSC	Female	II,III,IV	−0.210	.005	4	view →
BRCA	All	III,IV	−0.148	.008	3	view →
THCA	Male	All	−0.115	.016	2	view →
PAAD	Female	All	−0.054	.038	2	view →
CHOL	All	All	+0.136	.020	1	view →
KIRC	All	III,IV	+0.050	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

TEX12–BLCA

Open the BLCA breakdown →