TESMIN

Across TCGA patient cohorts, TESMIN mutation is significantly associated with the RNA expression of many other genes, with 2,799 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TESMIN-associated genes across cancer lineages are TRAJ52, MIR624, and RNA5SP86. Each is linked with TESMIN in more than 3 cancer types. Because this analysis shows association rather than direction, both TESMIN-to-partner and partner-to-TESMIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ52 grouped by TESMIN-low versus TESMIN-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TESMIN→partner) and Y-score (partner→TESMIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRAJ52 →	+0.883	+3.169	<.001	.004	3	4
COAD	MIR624 →	+0.585	+3.133	<.001	.004	3	2
COAD	RNA5SP86 →	+0.723	+4.557	<.001	.004	3	2
COAD	EI24P1 →	+0.120	+3.169	<.001	.004	3	2
COAD	RN7SL148P →	+0.224	+4.136	<.001	.008	3	2
COAD	MIR5190 →	+0.931	+3.343	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,799 associations by consensus.

TRAJ52 by TESMIN expression — COAD

Explore this box plot interactively →