TESC

Across TCGA patient cohorts, TESC protein abundance is significantly associated with the RNA expression of many other genes, with 14,796 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TESC-associated genes across cancer lineages are PTPRN2, PKDCC, and TESC-AS1. Each is linked with TESC in more than 4 cancer types. Because this analysis shows association rather than direction, both TESC-to-partner and partner-to-TESC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TESC versus PTPRN2 in LUAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TESC→partner) and Y-score (partner→TESC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PTPRN2 →	+1.200	+0.839	<.001	<.001	3	5
UCEC	PKDCC →	+1.546	+0.567	<.001	<.001	3	5
LUAD	TESC-AS1 →	+0.517	+1.117	<.001	<.001	3	5
COAD	CADPS2 →	+1.126	+0.849	<.001	<.001	3	5
LUAD	ATE1 →	+0.505	+0.847	<.001	<.001	3	4
UCEC	PPM1H →	+1.297	+0.817	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,796 associations by consensus.

TESC vs PTPRN2 — LUAD

Explore this scatter interactively →