TESC-AS1

Across TCGA patient cohorts, TESC-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,003 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TESC-AS1-associated GO terms across cancer lineages are Phosphatidylinositol biosynthetic process, Regulation of autophagy of mitochondrion, and Regulation of cell morphogenesis. Each is linked with TESC-AS1 in more than 15 cancer types. Because this analysis shows association rather than direction, both TESC-AS1-to-partner and partner-to-TESC-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol biosynthetic process grouped by TESC-AS1-low versus TESC-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TESC-AS1→partner) and Y-score (partner→TESC-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Phosphatidylinositol biosynthetic process →	+0.065	+0.246	<.001	<.001	2	16
STAD	Regulation of autophagy of mitochondrion →	+0.065	+0.246	<.001	<.001	3	14
STAD	Regulation of cell morphogenesis →	+0.058	+0.183	<.001	.001	2	15
ESCA	Glycerolipid biosynthetic process →	+0.062	+0.201	<.001	<.001	3	14
THYM	Retina development in camera-type eye →	+0.047	+0.228	<.001	<.001	3	13
STAD	Glycosylation →	+0.047	+0.159	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,003 associations by consensus.

Phosphatidylinositol biosynthetic process by TESC-AS1 expression — ESCA

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