TENT5B

Across TCGA cell cohorts, TENT5B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,842 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TENT5B-associated GO terms across cancer lineages are Positive regulation of purine nucleotide biosynthetic process, Positive regulation of nucleotide biosynthetic process, and Actomyosin structure organization. Each is linked with TENT5B in more than 9 cancer types. Because this analysis shows association rather than direction, both TENT5B-to-partner and partner-to-TENT5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of purine nucleotide biosynthetic process grouped by TENT5B-low versus TENT5B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TENT5B→partner) and Y-score (partner→TENT5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of purine nucleotide biosynthetic process →	+0.134	+1.661	.001	<.001	3	10
STOMACH	Positive regulation of nucleotide biosynthetic process →	+0.134	+1.661	.001	<.001	3	10
SOFT_TISSUE	Actomyosin structure organization →	+0.055	+1.088	<.001	<.001	3	9
BONE	Regulation of plasma membrane repair →	+0.343	+1.460	<.001	<.001	3	9
URINARY_TRACT	Regulation of mitochondrial membrane potential →	+0.087	+1.532	<.001	<.001	3	9
STOMACH	Positive regulation of ATP biosynthetic process →	+0.132	+1.661	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,842 associations by consensus.

Positive regulation of purine nucleotide biosynthetic process by TENT5B expression — STOMACH

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