TELO2

Across TCGA patient cohorts, TELO2 mutation is significantly associated with the RNA expression of many other genes, with 1,843 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TELO2-associated genes across cancer lineages are LINC02855, DDX11L1, and LINC02488. Each is linked with TELO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TELO2-to-partner and partner-to-TELO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02855 grouped by TELO2-low versus TELO2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TELO2→partner) and Y-score (partner→TELO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC02855 →	+0.060	+4.122	<.001	.009	3	2
LUSC	DDX11L1 →	+0.053	+3.286	<.001	.008	3	2
LUSC	LINC02488 →	+0.119	+3.650	.002	.006	3	2
LUSC	RNA5SP419 →	+0.432	+5.102	.002	.002	3	2
LUSC	RNA5SP420 →	+0.375	+4.309	.006	.007	3	2
UCEC	TUBGCP5 →	+0.360	+1.809	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,843 associations by consensus.

LINC02855 by TELO2 expression — LUAD

Explore this box plot interactively →