TELO2

Across TCGA pan-cancer cohorts, TELO2 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of TELO2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TELO2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TELO2 is over-expressed in tumor.

COAD, HNSC, and KIRP are the cancer types where TELO2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TELO2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+1.400	<.001	12	view →
HNSC	Male	III,IV	+0.761	<.001	12	view →
KIRP	All	II,III,IV	+0.890	<.001	11	view →
KIRC	Female	All	+0.611	<.001	11	view →
LIHC	Female	II,III,IV	+1.418	<.001	9	view →
STAD	Male	II,III,IV	+1.198	<.001	8	view →
LUAD	All	III,IV	+0.823	<.001	8	view →
LUSC	Male	II,III,IV	+0.834	<.001	6	view →
UCEC	All	III,IV	+0.738	<.001	6	view →
BRCA	All	All	+0.496	<.001	6	view →
CHOL	Male	All	+2.208	<.001	5	view →
BLCA	All	All	+0.379	.016	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

TELO2–COAD

Open the COAD breakdown →