DEAD/H-box helicase 11 like 1 (pseudogene)Genealiases: []
Q-omics provides the consensus-scored DDX11L1 profile across patient tissues and cancer cell-line models. DDX11L1 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, DDX11L1 is differentially expressed in 4, with the highest sampling consensus in HNSC. Additionally, DDX11L1 RNA expression shows 4,574 significant protein co-abundance associations, with the highest sampling consensus in OV. Together, these results highlight UCEC, HNSC, and OV as cancer lineages where DDX11L1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for DDX11L1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes DDX11L1 survival associations across molecular data types. DDX11L1 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible DDX11L1 RNA expression–survival associations across cancer types. High DDX11L1 expression shows unfavorable associations in UCEC, KIRP, LUSC, SKCM and KICH, but favorable associations in MESO. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify UCEC as the clearest survival context for DDX11L1 RNA expression.
This table summarizes DDX11L1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for DDX11L1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. DDX11L1 shows lower tumor expression in THCA and KIRP and higher tumor expression in HNSC and PRAD. The HNSC box plot shows higher DDX11L1 RNA expression in tumor versus normal tissue (log2 FC = +0.006, t-test p = .029).
This table shows molecular features associated with DDX11L1 in patient tissues and cancer cell lines. In patient samples, DDX11L1 shows the broadest associations at the RNA and protein expression levels, with OV recurring as the lineage with the largest associated feature set.
