Across TCGA patient cohorts, DDX11L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,441 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible DDX11L1-associated GO terms across cancer lineages are Regulation of DNA-directed DNA polymerase activity, NADH dehydrogenase complex assembly, and Mitotic DNA integrity checkpoint signaling. Each is linked with DDX11L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DDX11L1-to-partner and partner-to-DDX11L1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DDX11L1→partner) and Y-score (partner→DDX11L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Regulation of DNA-directed DNA polymerase activity →	+0.030	+0.005	<.001	.002	3	6
HNSC	NADH dehydrogenase complex assembly →	+0.022	+0.007	<.001	.003	3	5
OV	Mitotic DNA integrity checkpoint signaling →	+0.021	+0.031	<.001	<.001	3	5
LUSC	Ribose phosphate biosynthetic process →	+0.016	+0.008	<.001	.002	2	6
LUSC	Protein methylation →	+0.018	+0.013	<.001	<.001	3	5
READ	Homologous recombination →	+0.028	+0.028	<.001	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,441 associations by consensus.

Exploration

DDX11L1 survival (RNA) · tumor vs normal (RNA) · all DDX11L1 data types