TEC

Across TCGA patient cohorts, TEC protein abundance is significantly associated with the RNA expression of many other genes, with 2,329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEC-associated genes across cancer lineages are ACVR2A, PLA1A, and MFSD14B. Each is linked with TEC in more than 1 cancer types. Because this analysis shows association rather than direction, both TEC-to-partner and partner-to-TEC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TEC versus ACVR2A in PDAC, with a Pearson correlation of -0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEC→partner) and Y-score (partner→TEC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ACVR2A →	-0.689	-0.405	.002	<.001	3	2
UCEC	PLA1A →	+1.090	+0.498	.008	.008	3	2
OV	MFSD14B →	+0.748	+0.836	<.001	<.001	3	2
OV	STRBP →	+0.609	+0.564	<.001	.001	3	2
UCEC	YPEL4 →	-0.768	-0.529	<.001	<.001	3	2
UCEC	KIF5C →	-0.720	-0.501	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,329 associations by consensus.

TEC vs ACVR2A — PDAC

Explore this scatter interactively →